Animal Physiology

Animal Physiology

Expensive research animals require specialized anesthesia and surgical equipment that is designed for their physiological needs. WPI offers a broad range of laboratory equipment and research products designed specifically for small animal physiology.

  1. Analgesia
    Analgesia testing is a growing field. Before new pain killing pharmaceuticals are brought to market, they must undergo a host of efficacy studies involving some form of analgesiometry prior to any clinical trials.  The standard nociceptive threshold testing for preclinical trials involve mechanical, thermal and chemical stimuli with mice and rats. WPI offers a variety of such equipment.
  2. Anesthesia
    EZ Anesthesia is the system of choice for anesthetizing small animals, and it comes with a variety of choices. Animals to be anesthetized are placed in the acrylic induction chamber and the system delivers a precisely blended mixture of oxygen and isoflurane. An activated charcoal air filter canister at the top of the chamber releases safe, filtered air back into the room. A water-heated cage warmer or warming plate (ATC2000) is used to retain the animal body temperature while in the induction chamber. After the initial anesthetizing, the animal can be moved to the heated surgical water bed and positioned properly in the snugly fitted nosecone. A highly sensitive valve regulated by the animal’s breathing works with the nosecone to ensure non-rebreathing efficiency, and allow safe anesthesia for up to several hours. The breathing device also includes an air filter that releases safe, filtered air back into the room.
  3. Animal Temp Control
    Keeping anesthestized animals warm during research procedures is critical. WPI's ATC2000 Animal Temperature Controller is simple to operate, because its adaptive mode takes the guesswork out of temperature control so you can focus on the details of your own experiment.
  4. Blood Pressure Monitor
    Small animal blood pressure monitors used in a research laboratory can be invasive or non-invasive. For example, if you wanted to measure direct arterial and venous pressure, you could use an animal catheter and the BLPR2 system. For non-invasive blood pressure measurements, you could use the tail cuff monitor. Our IITC tail cuff monitor allows for tail movement and is designed to minimize stress to the animal.
  5. Physiology Accessories
    Here are the odds and ends animal physiologists requires.
  6. Stereotaxic Instruments
    Stereotaxic frames have been in use for animal research since the 1930s, and they come in a variety of forms. WPI offers stereotaxic frames and accessories like neonatal adapters, ear bars, probe holders and tooth bars. Are you looking for basic frames with single or dual arms, motorized and digital frames or parallel rail frames? We have frames for mice, neonatal rats, guinea pigs, rats and larger animals like monkeys or dogs. Special applications may require anesthesia gas masks, spinal adapters or a micro drill, which are all available here.
  7. Thermometers
    A variety of temperature probes for any research application Are you looking for a specific thermometer for your research application? We offer a variety. Flexible Teflon microprobes are used for implantation in tissue, in spectrophotometer cuvettes, rectally in neonatal mice, in water baths, PCR thermal cyclers, etc. Monitors animal rectal temperatures during surgical procedures and pyrogen testing Benefits Thermocouple wire used meets NIST standards (Certification is available for an additional cost) Applications Rectal temperature monitoring Instant read in tissue, semi-solids, small specimen and other materials When precise temperature measurements are required, WPI can provide you with a very accurate monitor and thermocouple microprobes. WPI monitors have both resolution and accuracy of 0.1°C in the 0-50°C range and are traceable to NIST standards, whereas, other competitive electronic thermometers have an accuracy that is usually to 0.5°C or worse. Furthermore, all our type T clinical probes are guaranteed accurate to 0.1°C, due to our stringent wire standards. These are five times more accurate than competitive probes made with regular “Special Limits” wire. 
  8. Ventilators
    These ventilators and carbon dioxide monitors are designed specifically for research laboratories for use with  rats, mice and other small animals.

Laboratory Equipment Designed for Small Animals

Some surgeries (for example, neuroscience) require precise positioning of an animal, and a stereotaxic frame is critical.

Anesthesia systems must also be specially designed for the small animal physiology in order to keep the animals and the researchers safe.

During surgery, researchers may monitor blood pressure and other vitals. You want a blood pressure monitor that will not stress your rodents and small animals.

It is also critical to keep your animals warm without burning them during a surgery.

WPI offers a broad range of equipment, surgical instruments and laboratory supplies that were designed for small animal physiology. Let us help you get the laboratory equipment that’s right for your research application.

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